Booster dose increases efficacy against Omicron, according to Moderna

Booster dose increases efficacy against Omicron, according to Moderna

Moderna vaccine booster dose increases neutralizing antibody level 37-fold against Omicron, reports report the company. The company made the announcement by releasing preliminary data Monday morning.

“The dramatic increase in COVID-19 cases due to the Omicron variant is of concern to all. However, these data showing that the currently authorized Moderna COVID-19 booster can increase neutralizing antibody levels by 37 times compared to the level before the booster dose is reassuring, ”said Stéphane Bancel, CEO of Moderna in a commentary. communicated.

These figures relate to the currently authorized booster dose, ie a dose of 50 µg. According to preliminary data from the company, a dose of 100 µg would increase the levels of neutralizing antibodies by approximately 83 times.

In addition, faced with the long-term threat posed by the immune escape of the Omicron variant, Moderna has also announced that it will continue to develop a vaccine against the Omicron variant. The latter should also be the subject of clinical trials in early 2022.

“To respond to this highly transmissible variant, Moderna will continue to rapidly advance a booster candidate specific to Omicron towards clinical trials, in case it becomes necessary in the future. ” also mentioned Stéphane Bancel.

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